~marginalrevolution | Bookmarks (29)

1) From the recent annual meeting of the American Society of Tropical Medicine & Hygiene (abstract 6949) we learn that the R21/Matrix-M malaria vaccine maintained it’s efficacy over 4 seasons. …Importantly, maintained high efficacy over four malaria seasons with only four doses is demonstrated, with no concerns to date of rebound in those who have […] The post Two Updates on the Value of...

During the pandemic, when vaccines doses were scarce, I argued for fractional dosing to speed vaccination and maximize social benefits. But what dose? In my latest paper, just published in PNAS, with Phillip Boonstra and Garth Strohbehn, I look at optimal trial design when you want to quickly discover a fractional dose with good properties […] The post Dose Optimization Trials Enable Fractional Dosing...

Your friends are not always good for you: The role of friends in the US opioid epidemic is examined. Using data from the National Longitudinal Survey of Adolescent Health (Add Health), adults aged 25-34 and their high school best friends are focused on. An instrumental variable technique is employed to estimate peer effects in opioid […] The post The Role of Friends in the...

…while one would certainly like to have these drugs available to these patients, if the price of these drugs doesn’t come down, you can make a good argument their cost will literally break Medicare. Why? Well, roughly 35% of Medicare patients are overweight or obese. Roughly 75% of people over 65 have coronary artery disease. […] The post The economics of semaglutide appeared first...

Knudsen: I don’t care that much about money, I’m a socialist! Here in Scandinavia, we teach our children teamwork from an early age. It’s not about the individual. And that’s how I am too. I have never asked for a raise in 34 years. DER SPIEGEL: You never got more money? Not even now? Knudsen: Yes, of course. […] The post Interview with Weight Loss Drugs Inventor...