Smad4 restricts injury-provoked biliary proliferation and carcinogenesis
ABSTRACTCholangiocarcinoma (CCA) is a deadly and heterogeneous type of cancer characterized by a spectrum of epidemiologic...
Physiological stress improves stem cell modeling of dystrophic cardiomyopathy
ABSTRACTHeart failure contributes to Duchenne muscular dystrophy (DMD), which arises from mutations that ablate dystrophin, rendering...
Face-valid phenotypes in a mouse model of the most common mutation in EEF1A2-related neurodevelopmental disorder
ABSTRACTDe novo heterozygous missense mutations in EEF1A2, encoding neuromuscular translation-elongation factor eEF1A2, are associated with developmental...
Piecing together the mosaic of rare skin diseases: an interview with Veronica Kinsler
Veronica Kinsler is a clinician scientist who has dedicated her career to researching rare paediatric skin...